Do Antibiotics affect performance?

Jumping in on this topic with my present experience. I currently have a badly impacted wisdom tooth which has me feeling generally awful and yesterday dentist has prescribed me a high dosage of metronidazole to clear the infection caused. These antibiotcs are well known for being rather unpleasant! This morning I was stupid and decided to still do my TR workout. Barely made it through the warm up (RPE was sky high!) before calling it, and did some easy Z1-Z2 instead. I’ve been feeling super strong lately, but this morning was horrendous. No idea if its the infection or the antibiotics… or most likely, both! But yes, I shaln’t be touching the bike for the rest of the week that’s for sure.