From Inside Exercise #68…I thought that was interesting. I already knew that some things like berberine or metformin will block training adaptation…at the mitochondria. It was very interesting to hear Derave state that antihistamine can also block training adapation and inhibit glycogen resythesis.
One more thing to keep in mind, I guess. But I think if you are really suffering from allergies, NOT using antihistamine can just flat out block training! So probably just better to take them for relief and say, ‘Oh well!’
yeah, I stopped taking them June-August, but then had to restart again in September and my nose was still running like a faucet. Sucks. Another reason I focus on building fitness during ‘winter’ in NorCal. Finally, we are cheap and run the thermostat low, inside temps drop to 60F / 16C at night in our house and its perfect sleeping weather. Sleeping in cool 60F temps might not be an ice bath, but that and training outside in 40-60F ‘winter’ weather sure seems to kick the body into growth mode.
I’ve been using nasacort daily, which really helps me. This was recommended by an asthma and allergy doctor. I think I’m good since it’s not an antihistamine!
“ Triamcinolone Nasal Spray. Nasacort® is a brand of triamcinolone . It treats allergy symptoms like sneezing and a runny nose. It works by decreasing inflammation in your nose to help you breathe easier.”
Maybe I’m in the clear maybe it’ll help you guys also!
I have asthma and allergies. I have tried everything … but this really cuts down sinus drainage. Atrovent (ipratropium bromide). It is prescription but your doc should have no trouble prescribing it. Long term Xyzal and others have long term side effects.
Honestly the best thing I’ve done is daily exposure to my biggest problems (grasses, trees, cats). I know that sound wacky but avoiding outdoors and cats in the house, well it just made my allergies worse. My theory was, why pay for allergy shots if f I can do it myself, everyday, for free
I added astepro spray this summer to my regimen. It was prescription until a year or 2 ago. Helps a ton with my allergies. Not the cheapest spray but it also shouldn’t have the systemic effects of taking antihistamine pills.
Well this is me, as I have posted when this has come up before. As well as nasal/ breathing/ asthma issues I also have eczema, so I take them for all my fecked up immune system. And when I’ve had bad flare ups of my skin, it can definitely hamper training with poor sleep and the body fighting the infection. So I go with anti-histamines the lesser of two evils.
And yes, I do have daily exposure to triggers, with 2 cats in the house, horses in the fields, surrounded by trees (tree and grass pollens my hayfever issues!).
Been trying to get my GP to switch me to steroids - trimcinalone didn’t seem to hamper Wiggins when he had the TUE for allergies…
Meclizine inhibits mtor (it even extends life span in genetically heterogeneous mice). Ampk activation is needed for endurance adaption. Ampk can only be elevated when mtor activity is low. So if you need an antihistamine maybe try meclizine
This is surprising and potentially explains a lot about my most recent season. Since I started training seriously I’ve only ever really needed antihistamines for 3-6 weeks in Spring/Summer but in August 2022 I developed Eczema for the first time. Dermatologist is pretty sure it’s secondary to skin allergy reactions to one or more environmental and/or food triggers which we haven’t been able to pinpoint yet. That means for the last year I’ve been on antihistamines almost constantly (in addition to other treatment interventions).
It has definitely been a lot harder to progress in my training this year than in any previous season. I dismissed it as an age thing - just figured it was part of being closer to 40 than to 30 now.
This is making me think about it all a bit differently…
Just listened to the podcast segment - they’re pretty clear they don’t know the effect at “normal” anti-histamine allergy intake. That’s what they’re researching now. So I’ll be carrying on anyway, given it’s still only possible effects.
They worked, but I hated going in once a week. And 5-10 years after the last set of shots, I would occasionally get hive like bumps at old injection sites on the upper arm. A normal immune system can be quite good at doing its job, and thats leveraged as the basis for vaccinations. IMHO avoiding allergens had the effect of reducing the effectiveness of my immune system. And again, IMHO, all I’ve done is micro-dose allergens to increase the effectiveness of my immune system. My allergies can be quite severe, so I do find taking antihistimanes during the worst months to also help.