I’ll add to this.
I also use Favero Assioma (DUO), and TR on a Macbook with ANT+ dongle. Been doing so around 9 months now.
I’ve found that it’s best to put power smoothing on the same interval as my head unit (a trusty Garmin 500). That unit only allows 3s or 10s smoothing (doesn’t have 5s), so I’ve chosen 3s and set TR to the same.
Yes, the power can be “jumpy” at that interval but I would recommend persisting with it. It’s made a huge difference to my pedaling technique and over time the “jumps” have become very minimal. I can ride to within a +/- 8w range from target power pretty consistently. Think of it as technique practice.
Also, with ANT+, you can have your head unit listening to the same broadcast as your Macbook. Psychologically that is useful - you’ll be looking at the head unit when outdoors, and if you’re familiar with those numbers on that unit you can measure and control your ride that much better…