As others have said, yes it can work - my regular riding buddy runs an oval outer ring on an otherwise standard Di2 setup. My experience with Q rings is that derailleur position needs to be spot on, and even then you can get some chainsuck between the 2 rings every now and again. If I were running 1x, I’d have an oval chainring every time, as for me I think they offer some advantages, but as a 2x, my experience was the shifting wasn’t great.