There seems to be some conflation between different conditions vs. what is a very specific condition - a saddle sore.
A saddle sore is an infected pore or hair follicle that is swollen and painful, sometimes hard like a cyst, sometimes softer like a pimple. This is the reason many are suggesting hygiene as a primary line of defense against a saddle sore.
A chamois, by itself, should not be able to cause a saddle sore. It may well cause irritation or chafing, which can obviously be very painful and prevent riding., but that is not a “saddle sore”. I have had a couple pairs of bibs from a well-known clothing manufacturer that have caused me to get an irritation on my butt cheek from the edge of pad,a “quarter moon on my half moon” as I always call it. Doesn’t always happen, but does occasionally. That is definitely not a “saddle sore”.
Many years ago, Frankie Andrew had a massive saddle sore during the Tour and they had to hack away part of his saddle just so he could sit on his bike. Was unsuccessful in finding a picture of it, but they literally cut away ~1/4 of his saddle. (Side note - if you google “Frankie Andreu, Saddle Sore” the Images tab comes back filled with pictures of Lance Armstrong. 
).
ETA - I brought up this distinction because they are very different things and are not treated remotely in the same way. If the OP is dealing with a true saddle sore, all the suggestions re: chamois, etc aren’t going to help and could send him down rabbit holes.