Thinking of mixing in a deeper wheel on the rear vs front. Yes or No?
Thanks guys
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Hard to say without knowing what bike it’s for or where you ride or how you ride or anything else, so, yes?
I updated the Title it is a 2021 Madone SL6
Rolling Terrain Louisville KY
I’m 145lbs nekkid, 155 geared (guess as I have never weighed in full kit) and run the Aeolus XXX 6 all the time on my 2018 Emonda. I get a little of front waver in strong crosswinds, but they are manageable as long as you don’t panic and lock up. Just let the bike float under and you are fine.
Otherwise, I have nothing negative to say about them. They are just plain fast everywhere, despite my concerns about the front depth before I got them. I considered the 4/6 split, but went full race and am happy to have done so.
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Sure…not the most aero option, but certainly nothing wrong with it.
Aesthetically, no way I could do that, though…my OCD would lock me up. 
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Just did that and I LOVE it! DT Swiss 1100 48/62 and they are simply amazing. It’s quite common to mismatch front and rear, so I’d go for it. Mine are really shockingly good in strong crosswinds and simply climb incredibly well. The look is very cool IMO and function is great!
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Thanks for the input!
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After doing Triathlon I actually think it looks pretty good. But yes I have concerns I will regret it. Ordering today still undecided.
You won’t regret if once you ride. The pro triathlete on our team has stated how great the mix is. If you go too deep on the front, strong crosswinds can be sketchy, especially at your weight. The rear can be far deeper as it is far less effected by side winds and helps make you as a package more aero. It’s a very fun and fast ride.
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Nah…if you think it looks good, you won’t regret it. The aero difference will be minimal and will ride just fine.
For general riding, no reason not to. I’m a lighter rider and I run a shallower (but not shallow) front wheel. I’ll take the crosswind confidence over the aero loss. For crits, not so much but I don’t really do those. At my previously local to me outdoor velodrome, I switched to a 40mm front + rear disc and didn’t miss getting pushed uptrack in turn 2 on windy days!
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Given my experience with 62.6mm Hadrons when I was 143lbs and my experience now on the TT bike with a disc rear and the 62.5mm fron mt, weighing in at 128lbs; and my last TT in 30-40mph gusts where I used a 35mm front. I’d say go for it 
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I’m 155-160lbs and run XXX 6 front and rear on my 2021 Domane, not exactly the same but close enough. I’ve had no problems running these and don’t have any regrets about going deeper on the front. The XXX wheels are very stable. But… a) I’ve been running 50mm+ wheels for more than 10 years and am pretty familiar/comfortable with how they handle; b) I also live a fair way inland so, while it gets windy on occasion, I don’t have to deal with particularly strong winds on a regular basis; and c) I don’t race in overly technical conditions i.e. no sustained hard braking/cornering/accelerations.
So, XXX 6 is fine for some people/situations, 4F and 6R is fine for others.
I’ve also run slightly shallower front wheels when using particularly deep wheels (65-90 on the rear) and it makes sense, I’m not averse to the idea you’re considering.
p.s. I’ve also got XXX4’s on my Emonda. TBH, it’s next to impossible for me to tell the difference in how the wheels handle, 40kph+ crosswinds while cornering kinda stuff so don’t overthink it
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