Thanks @AJS914
I appreciate your response with the linked research papers and will take a closer look.
We are all looking for the magic bullet and sometimes people like the much respected Dr Attia comes along and provides it for us.
His book outlive is such a good read and the VO2 theory is backed up by so many others.
I will carry on with the researching and you have opened my eyes a little wider for some more investigation and thank you for that 
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