I always thought steeper seat tube angle is preferable for everything that you pedal up and slacker head tube angle for everything going down. So without having ridden any of the two bikes just by comparing geo-charts, I personally would go with the cannondale.
If you have the chance to testride both bikes, I’d suggest you do that. And if you can’t decide after riding both bikes, I’d say go with the bike you like better. Why? Because You’ll enjoy riding it more.
edit: was looking at the wrong bike (Trek Fuel SL), my bad.