There is no answer. Here are just a few factors:
- Do you want to go fast uphill or downhill?
- What terrain do you want to ride?
- What is the weather like? Do you encounter mud or wet forest floor? Or is it arid and you are fighting the antigrip dust that is scattered across the Chilean Andes?
- How much puncture protection do you need?
Tires, especially offroad tires, are always a compromise.