Disc Brakes and Pads that *DON'T* squeal?

Based on everything you’ve tried and the fact you’ve replaced calipers more than once I’d echo @Gnome and suggest checking whether the mounts need to be faced. I can imagine if the facing is bad enough it could even make leaky seals more likely (if they’re forcing the piston to sit wonky in the caliper) but I suspect it would have to be unusably bad before that would happen.

Also worth taking a page from @batwood14’s anecdote and doing a really thorough investigation to rule out some really weird unexpected contamination source like a third party with cleaning spray when you’re not even home.

And I’ll echo a few different warnings about being too obsessive/proactive in trying to address issues too, but not because of additional contamination risk as suggested by others: The lesson that took me longest to learn is that all of the ‘fixes’ really only get you about 90% of the way there. The only way I’ve ever found to truly finish the job is just to ride hard for a couple hours on a really dry day, and that alone is also enough to deal with quite a lot.

Here’s how I phrased it in a different thread (shamelessly including the endorsement I got from another user :grin:)

And another version of much the same info that I wrote out for someone in my club’s facebook group:

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